Our aim is to comprehensively and quantitatively characterize the mechanobiological features of primary human mammary gland in order to identify new regulatory mechanisms of breast cancer invasion and resistance to therapy. The research of the lab is focused on mechanotransduction ie. the mechanical links between the extracellular environment and the cell interior.

Freshly isolated primary human mammary epithelial cells in a 3D collagen gel (green CNA35-GFP, red SiR-Actin; Imaged with spinning disk confocal microscope, frame interval 30min)

A mixture of antibody-labelled primary HMECs (scale bar 20┬Ám).